Gene description for Ruvbl1
Gene name	RuvB-like AAA ATPase 1
Gene symbol	Ruvbl1
Other names/aliases	2510009G06Rik Pontin52 Tip49a
Species	Mus musculus
Experiment description of studies that identified Ruvbl1 in Myeloid-derived suppressor cells
1 Experiment ID 678 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 29951053    Organism Mus musculus Experiment description Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Authors Zör M, Zhao K, Kutlu N, Bauer N, Provaznik J, Hackert T, Schnör M. Journal name Front Immunol Publication year 2018 Sample Myeloid-derived suppressor cells Sample name In-vitro- Alopecia areata affected C3H/HeJ mice BMC derived Isolation/purification methods Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
2 Experiment ID 1126 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24295599    Organism Mus musculus Experiment description Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Authors Burke M, Choksawangkarn W, Edwards N, Ostrand-Rosenberg S, Fenselau C. Journal name J Proteome Res Publication year 2014 Sample Myeloid-derived suppressor cells Sample name Conventional MDSC's-BALB/c mice injected with 4T1 cells Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140063: EV-METRIC:71%
3 Experiment ID 1127 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24295599    Organism Mus musculus Experiment description Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Authors Burke M, Choksawangkarn W, Edwards N, Ostrand-Rosenberg S, Fenselau C. Journal name J Proteome Res Publication year 2014 Sample Myeloid-derived suppressor cells Sample name Inflammatory MDSC's-BALB/c mice injected with 4T1 cells expressing IL-1. Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140063: EV-METRIC:71%